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OECD 487

Biological evaluation of medical devices

In Vitro Mammalian Cell Micronucleus Test

The In Vitro Mammalian Cell Micronucleus Test detects micronuclei in the cytoplasm of interphase cells. These micronuclei may originate from acentric chromosome fragments or whole chromosomes that are unable to migrate to the poles during the anaphase stage of cell division.

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